研究開発・学会発表

10月のおはな

Fertility and Sterility

学会名

Fertility and Sterility

日・場所

Vol. 93, No.6, April 2010

タイトル

A healthy birth after intracytoplasmic sperm injection using ejaculated spermatozoa from a patient with Kartagener’s syndrome

発表者名

Yukiko Matsumoto a, Sakae Goto a, Hiromi Hashimoto a, Shoji Kokeguchi a,

Masahide Shiotani a,Hiroshi Okada b



a Hanabusa Women’s Clinic, Kobe, Japan

b Dokkyo Medical University Koshigaya Hospital, Koshigaya, Japan

Objective: To report a healthy birth that was achieved by intracytoplasmic sperm injection (ICSI) using ejaculated spermatozoa from a patient with Kartagener’s syndrome.

Design: Case report

Setting: Private infertility clinic

Patient(s): Couple with male factor infertility due to Kartagener’s syndrome

Intervention(s): Intracytoplasmic sperm injection with ejaculated sperm

Main outcome measure(s): Semen characteristics, sperm motility, fertilization, pregnancy, and birth after ICSI.

Result(s): With ejaculated sperm, the fertilization rate were 73% in the first stimulation cycle and 100% in the second cycle. Intracytoplasmic sperm injection was successful. The pregnancy resulted in birth of a single healthy child.

Conclusions: With ejaculated sperm, successful pregnancy after ICSI in couples with Kartagener’s syndrome is possible. Kartagener’s syndrome is a heterogeneous group of disorders with similar clinical presentations, and treatment should be individualized depending on sperm motility.

Key Words: Kartagener’s syndrome, ICSI, ejaculated sperm