研究開発・学会発表

12月のおはな

ASRM

学会名

ASRM

日・場所

平成23年10月15日(土)~10月19日(水) フロリダ州オーランド

タイトル

Outcome of stimulation of endometrium embryo transfer (SEET): from an analysis of 2,168 single frozen-thawed blastocyst transfer cycles

発表者名

Hiromi Ogata, Seiji Ogata, Nobuhiko Kataoka, Shoji Kokeguchi, Masahide Shiotani

Hanabusa Women’s Clinic, Kobe, Japan

OBJECTIVE:

SEET is a variant method of blastocyst transfer, which is characterized by the injection of the embryo culture supernatant into the uterus before blastocyst transfer. We reported that SEET improved the implantation rate and the pregnancy rate in single frozen-thawed blastocyst transfer cycles (Fertil Steril 2007, 2009). Thereafter, we primarily select SEET method in frozen-thawed blastocyst transfer cycles. In this study, we retrospectively analyzed the outcome of SEET cycles in our ART center.

 
DESIGN: Retrospective analysis.
 
MATERIALS AND METHODS:
In this study, we collected a total of 2168 cycles of SEET cycles between January 2009 and December 2010. SEET method was performed as previously described (Fertil Steril 2007). We stratified data according to age, previous ART history, and morphological grade of blastocyst, and then investigated the clinical outcome in each group.
 
RESULTS:
The average age was 36.3, the average number of previous ART cycles was 2.4, and the total clinical pregnancy rate was 38.4%. The more previous ART cycles led to the lower clinical pregnancy rate (Table1). The clinical pregnancy rates of patients under 37 years of age and above 38 years of age were 45.1% and 27.8%, respectively. The clinical pregnancy rates after high grade blastocyst transfer and low grade blastocyst transfer were 57.0% and 31.9%, respectively.
 
CONCLUSION:
In this study, we showed the good clinical outcome of SEET. SEET is a simple and effective method for single blastocyst transfer.