研究開発・学会発表
診療・治療
IFFS/JSRM International Meeting 2015
- Outcome of warmed cryo-preserved surplus embryo transfer for second baby after successful conceived with TESE-ICSI
- 平成27年4月26日(日)～29日(水) 横浜
- IFFS/JSRM International Meeting 2015
- Shoji Kokeguchi1), Hiromi Ogata1), Seiji Ogata1), Yukiko Matsumoto1), Tomomoto Ishikawa2), Kohei Yamaguchi2), Masahide Shiotani
Hanabusa Women’s Clinic1) Fertility Clinic Osaka2)
Objective
To assess the rate of pregnancy of warmed cryopreserved embryo transfer for second baby after successful TESE-ICSI. And to compare this outcome to the outcome of standard IVF/ICSI.
Materials and method
46 couples who performed simple TESE and cryopreservation followed by ICSI performed between 2007 to 2011 were evaluated. This study is a retrospective study. We followed couples who came to our clinic to wish for a second baby. The mean couples age, number of ART cycles until the first delivery and interval between first baby delivery and next embryo-transfer were evaluated.
Results
There were no significant differences between couples who conceived using surplus embryos and those that were unable to conceive with the criteria above. Couples who conceived had a greater number of surplus embryos (5.2 vs 2.0) and more expanded blastocysts (2.3 vs 0.8) with preserving first successful ART than those who could not conceive. 19 out of 46 couples (41.3%) conceived by surplus embryo(s) with TESE-ICSI. This rate was the same as that of couples using standard IVF. The couples who had conceived but could not obtain no surplus embryo tried to performed ART for a second baby conceived 30.7% (4/13) with mean 3.2 times ART. They had a tend to be late to start treatment for second baby.
Conclusion
couples who previous undergone successful TESE-ICSI may have a surplus of cryopreserved embryos. Our results indicate that the transfer of these embryos gives positive pregnancy rates similar to those obtained from traditional IVF.
